Claude security directory

Helix GenoSphere

Published by Helix

Medium risk

Bring Helix GenoSphere™ — a growing research clinico-genomic dataset of more than 500,000 exome-sequenced participants with linked longitudinal EHR data — directly into Claude. Query gene-level carrier counts and pathogenic variants, determine target genes on curated panels, search standardized medical vocabularies (conditions, drugs, labs), and obtain privacy-protected patient counts for any concept. All responses are aggregated and statistically de-identified, with small groups suppressed to protect participant privacy. A read-only window into population-scale genomics, no SQL required.

Security assessment

Plutonium assessed this web connector for permissions, capabilities, and security-relevant behavior.

  • Reads your private information: The connector can query sensitive clinico-genomic and longitudinal EHR-derived data (even if returned only in aggregate), which could still reveal sensitive insights about populations or cohorts a user is interested in.
  • Sends your data to outside companies: Queries and parameters you provide (e.g., genes, variants, concepts of interest) are sent to Helix GenoSphere’s hosted service, disclosing research intent and potentially sensitive investigative context to a third party.

Available capabilities

This add-on exposes 5 tools or capabilities.

  • get_variant_frequency
  • check_gene_availability
  • get_dataset_overview
  • search_concepts
  • get_patient_count

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