{"generated_at":"2026-08-17T10:36:11+00:00","item":{"added_at":"2026-07-05","analysis_method":"capability_triage","category":"Web Connector","description":"Bring Helix GenoSphere™ — a growing research clinico-genomic dataset of more than 500,000 exome-sequenced participants with linked longitudinal EHR data — directly into Claude. Query gene-level carrie","did":"ant-dir-helix-genosphere","homepage_url":"https://www.helix.com","icon":"https://helix.com/favicon.ico","id":"ant.dir.helix.genosphere","installs":13435,"last_scanned":"2026-07-05","license":"","long_description":"Bring Helix GenoSphere™ — a growing research clinico-genomic dataset of more than 500,000 exome-sequenced participants with linked longitudinal EHR data — directly into Claude. Query gene-level carrier counts and pathogenic variants, determine target genes on curated panels, search standardized medical vocabularies (conditions, drugs, labs), and obtain privacy-protected patient counts for any concept. All responses are aggregated and statistically de-identified, with small groups suppressed to protect participant privacy. A read-only window into population-scale genomics, no SQL required.","name":"Helix GenoSphere","plutonium_url":"https://plutonium.pluto.security/detail.html?planet=claudesec&did=ant-dir-helix-genosphere&utm_source=plutonium_analysis_skill&utm_medium=claude_skill&utm_campaign=connector_risk_assessment","publisher":"Helix","publisher_url":"https://www.helix.com","repository_url":"","risk":"medium","risk_severity":"medium","security_risks":[{"description":"The connector can query sensitive clinico-genomic and longitudinal EHR-derived data (even if returned only in aggregate), which could still reveal sensitive insights about populations or cohorts a user is interested in.","risk_type":"reads_private_data","severity":"medium","title":"Reads your private information"},{"description":"Queries and parameters you provide (e.g., genes, variants, concepts of interest) are sent to Helix GenoSphere’s hosted service, disclosing research intent and potentially sensitive investigative context to a third party.","risk_type":"forwards_data_to_third_party","severity":"low","title":"Sends your data to outside companies"}],"signature_status":"unknown","source_code_reviewed":false,"tags":["forwards_data_to_third_party","reads_private_data"],"tools":[{"description":"Returns aggregated allele/variant frequency or carrier counts for a specified genetic variant across the dataset.","name":"get_variant_frequency"},{"description":"Checks whether a given gene is available/covered in the dataset and/or curated panels.","name":"check_gene_availability"},{"description":"Provides a high-level summary of dataset scope, coverage, and available data domains.","name":"get_dataset_overview"},{"description":"Searches standardized medical vocabulary concepts (e.g., conditions, drugs, labs) for matching terms.","name":"search_concepts"},{"description":"Returns privacy-protected aggregated patient counts for a specified concept or cohort definition, with small counts suppressed.","name":"get_patient_count"}],"tools_count":5,"type":"web_connector","url":"https://claude.ai/directory/cc609c18-f6f5-44a0-ac77-6150b9d7b439","uuid":"cc609c18-f6f5-44a0-ac77-6150b9d7b439","version":""},"query_key":"helix genosphere","schema_version":1,"status":"match"}